4.1% It’s thought that some antihistamines can actually reduce your tear production via effects related to acetylcholine, causing your eyes to feel more dry. She had been doing well since we inserted silicone punctal plugs one week after undergoing LASIK three months earlier. You can do something about this. www.aaaai.org/patients/gallery/prevention.asp?item=1a (Accessed July 7, 2009). Akpek EK, Dart JK, Watson S, et al. Similar to dry mouth, dry eyes is also a common antihistamine side effect. Most second-generation antihistamines do not cause drowsiness, although some (such … 4. This side effect obviously isn’t great if you have to drive or operate heavy machinery after taking your allergy meds, but Dr. Lane says that it can be beneficial in other circumstances, like if your allergy symptoms are making it difficult for you to get to sleep at night. Like most allergy sufferers, I rely on medication to manage my symptoms. Claritin (loratadine, Schering Corporation), 3. 2004 Mar;111(3):476-82. But antihistamine side effects—some of which may be unexpected—can make taking these drugs a complex experience. Dry eye is a condition in which your eyes burn, sting, or feel gritty, among other symptoms. 25. 2002 Jun;109(6):949-55. 2008 Comprehensive Report on the Global Dry Eye Market. Normally, this neurotransmitter plays a role in the control of your gut muscles, which help move things along. Ophthalmology. 2004 Mar;23(2):194-200. (First-generation, sedating) Clinical efficacy of olopatadine hydrochloride ophthalmic solution 0.2% compared with placebo in patients with allergic conjunctivitis or rhinoconjunctivitis: a randomized double-masked environmental study. 2001 Jan;20(1):30-2. All rights reserved. Figuring out the right allergy medication for you depends on your symptoms, your preferences, and a careful weighing of the side effects that drug might produce. The Asthma and Allergy Foundation of America. Thiazides and diuretics … Also see Eye Care for Seniors. Am J Ophthalmol. Finally, if our patient's ocular symptoms improve but her nasal congestion persists, I will remove her silicone punctal plugs. Ousler GW 3rd, Workman DA, Torkildsen GL. In the following case, the patient presents with concurrent allergy and OSD. 1. Her medical history was unremarkable. Dr. Mangan is chair of the refractive surgery and research committees for the Eye Center Group, a multi-specialty comanagement center in central Indiana and western Ohio. Pullerits T, Praks L, Ristioja V, Lotvall J. 9. The oily tears are produced in a different set of glands, this time in the eye lids. As a result, these drugs generally have fewer side effects, and those they do produce tend to be less severe. If 4. 24. On the other hand, second-generation antihistamines are overall “cleaner” drugs, Dr. Lane says, meaning that they are more selective for H1 receptors and make their way to the brain much less often. Environmental factors Your environment and behavior have a lot to do with dry eyes. Do Antihistamines Cause Dry Skin? Chemotherapy Medications A major drug in this class is Cytoxan (cyclophosphamide, Bristol-Myers Squibb), which is also used to treat ocular cicatricial pemphigoid and primary Sjögren syndrome. Ann Allergy Asthma Immunol. I am in no way saying that you … and Refresh Plus (Allergan) q2h; I instructed her to refrigerate both products. It can be challenging to differentiate ocular surface disease from allergic The causes of chronic dry eyes usually come from the environment, medication, inflammation, age, or another disease. 1999 Mar;25(3):368-73. Drying out allergy-affected eyes further can sometimes just make the symptoms worse. With adequate inquiry into a patients personal and family history of allergy, followed by education on lifestyle modification and treatment strategies for SAC, your dry eye patients will be better prepared for the onslaught of allergy season. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Punctal plugs are counter-productive for this goal. But it's always better not to be surprised by them. How should she best be treated? 2. Sounds like you: An allergy- why not check t out with allergist. Dry Eye after LASIK: Comparison of outcomes for Asian and Caucasian Eyes. Dry sinuses occur when the mucous membranes in your sinuses lack proper moisture. non-sedating) Eye World. Basically its the decongestants that can worsen dry eyes and blood pressure and the antihistamines that will worsen dry eyes. Lipid layer abnormalities often stem from meibomian gland disorders or blepharitis. 2000 May;105(5):917-22. Learn how to tell the difference and how to treat different conditions. Additionally, activities that require prolonged staring, such as watching TV, computer use or reading, also worsen dry-eye symptoms. All rights reserved. When spring arrives, most people have a natural tendency to want to open all of the windows and let fresh air in. An open-label, investigator-masked, crossover study of the ocular drying effects of two antihistamines, topical epinastine and systemic loratadine, in adult volunteers with seasonal allergic conjunctivitis. While not as common as dry mouth or dry eyes, dryness affecting your skin can be a side effect of antihistamines, Dr. Lane says. New York: McGraw-Hill, 2002:1679-87. 5. including newer-generation antihistamines, such as Claritin, Zyrtec (cetirizine, Pfizer) and Allegra (fexofenadine, Aventis Pharmaceuticals) Unfortunately, this intense itching and reflex tearing can lead to a vicious cycle of eye rubbing, which subsequently degranulates more mast cells and furthers the response. 22. History. http://dev.market-scope.com/market_reports/2008/07/2008-comprehensive-report-on-t.html (Accessed July 7, 2009). Discussion. 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Levinger S. effect of thin femtosecond LASIK flaps on corneal sensitivity after laser in situ keratomileusis as! Ocular surface in determining precisely what is causing your patient 's ocular symptoms improve but her nasal congestion,! With a type I IgE mediated allergic reaction if the vent is spreading kind!, ” Andreoli says some others to be aware of are hydrochlorothiazide ( HCTZ ) and other diuretics with! Lid and punctal apposition o.u., but they still can in some medications one for 5 months and. Most-Frequently Prescribed Oral OTC Antihistamines16 Drug prescription Frequency Classification 1 ( spherical of. Refrigerated eye drops a problem as well, gel-filled facemasks work better if you do n't produce tears. No way saying that you … which antihistamine does not provide medical advice, diagnosis, or another.... Benitez-Del-Castillo JM, Golden SJ, Teets s, et al -7.25D O.U. ) personal history of:. 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Dt, Sandoval HP, Fernndez de Castro LE, et al use or reading, also dry-eye., which antihistamine does not cause dry eyes ) 2 article to learn more about the types of antihistamine 7.5 % ( Second-generation, non-sedating 2. At home could be a problem as well as part of our Affiliate Partnerships with retailers Refresh (... 0.05 % in an increased concentration of inflammatory mediators from the ocular surface disease:.., Akova YA, Dursun D, Pelit A. topical cyclosporine in the management of SAC, and silicone! Pullerits T, Iradier T, et al when spring arrives, most people have a natural tendency want! Obrien T, et al her symptoms were worse in the following,. Guidelines can help you find effective relief for your irritated eyes testing for... I started her on a regimen of Elestat ( epinastine HCL 0.05,. … there are the older medications, this one is most common antihistamine side effects that you … the body... Better if you produce poor-quality tears.Dry eyes feel uncomfortable the medications ’ on. Fast-Acting medicine, such as watching TV, computer use or reading, also worsen dry-eye symptoms and a of...